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K2F and K2M in Full: Composition and Rationale of the Primary INET Group

Part 3 of our Deep GUNA Research series, for practitioners.

This article is written for a practitioner audience and draws directly on GUNA's own published research. It is educational in nature and does not replace clinical judgement or personalised medical advice.

The primary group of INET medicines carries the letter F for female patients and M for male patients next to the brand name: K2F and K2M. These are the basic INET medicines, and every secondary and tertiary product in the range — covered later in this series — is built on the same underlying structure.

Full Composition

K2F and K2M contain suis organotherapics of the neuroendocrine axis in decimal dilutions D6/D12/D30/D200.

K2F (dilutions D6/D12/D30/D200) K2M (dilutions D6/D12/D30/D200)
Glandula pinealis suis Glandula pinealis suis
Melatonin Melatonin
Hypophysis suis Hypophysis suis
Hypothalamus suis Hypothalamus suis
Glandula Thyreoidea suis Glandula Thyreoidea suis
Glandula Thymus suis Glandula Thymus suis
Pancreas suis Pancreas suis
Ovarium suis Testis suis
Corpus luteum suis —
Glandula suprarenalis suis Glandula suprarenalis suis

The one deliberate addition to this glandular sequence is Melatonin, combined specifically with Glandula pinealis suis. GUNA chose this pairing to strengthen neuroendocrine activity and obtain the optimum therapeutic effect — pairing the pineal gland's own tissue with the hormone it is best known for producing. Their tropism is clearly glandular, and their action can be described as "re-starting" neuroendocrine functionality.

Posology

10 drops, 2-3 times a day. Do not exceed the maximum daily dose of 30 drops.

Why the Composition Follows the Axis So Closely

This structure mirrors the neuroendocrine-immune chain covered in the first article of this series almost gland for gland: cerebrum, pineal gland, hypophysis, thyroid, thymus, pancreas, the gonads, and the adrenal glands — each one a checkpoint in the interconnected chain linking the central nervous system to the endocrine and immune networks. Where a chronic pathology has caused deregulation of neuroendocrine homeostasis at the receptor level, K2F and K2M are designed to work through that entire chain at once, rather than targeting a single gland in isolation.

This is also why K2F and K2M are described as the primary group — the foundational layer that Senectus F/M and K2F-DIA/K2M-DIA, covered in the next two articles, are built on top of. Where those later groups add single homeopathic remedies, vitamins or diabetes-specific adjuncts for more particular presentations, K2F and K2M represent the basic, broad-spectrum starting point: restoring the functional integrity of the axis itself.

Clinical Scope

Because K2F and K2M work across the whole neuroendocrine axis rather than a single organ, GUNA's clinical experience with the two products spans an unusually wide range of chronic, degenerative presentations — from functional disorders of the menstrual cycle and climacteric syndrome, to degenerative arthropathy and osteoporosis, to andropause and anxious-depressive syndrome in the elderly. The full indications list for INET as a whole is covered in the previous article in this series.

The next article looks at Senectus F and Senectus M — the secondary group of INET medicines, and the full rationale behind everything GUNA added to the basic K2F/K2M structure for the physiology of ageing.


Featured products

Guna K2F
Guna · INET Primary Group
Guna K2F
Basic INET compound restarting neuroendocrine function in women.
Guna K2M
Guna · INET Primary Group
Guna K2M
Basic INET compound restarting neuroendocrine function in men.

Explore the full Guna Endocrinology range — INET compounds and neuroendocrine support built on GUNA’s PNEI research.

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Related reading

Source: GUNA, *From Homotoxicology to INET*, "The Primary Group of Medicines."

Tags: Deep Guna Research, Guna Articles, K2F, K2M, Neuroendocrine Axis

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The information provided by United Remedies is for general education and is not medical advice. Homeopathic remedies are used within a tradition of self-care and are not a substitute for professional diagnosis or treatment. If symptoms are severe, persistent or worsening, please consult a qualified health professional.