Part 2 of a two-part Deep GUNA Research series on how GUNA's biotherapy remedies — cytokines, hormones and neuropeptides, and growth factors — are dosed and selected in practice.
This article is written for a practitioner audience and draws directly on GUNA's own published dosing-guide reference material. It is educational in nature and does not replace clinical judgement or personalised medical advice.
Part 1 of this series covered the two prescribing strategies GUNA uses across cytokines, hormones and neuropeptides, and growth factors — the lab-led aetiological approach, and the simpler, symptom-led symptomatological approach. This article is the full A–Z reference behind that second approach: GUNA's own symptom-to-remedy correlations index, covering every presenting symptom or condition its dosing guide cross-references back to a specific low-dose biotherapy remedy.
How to Use This Index
Each row below reflects a symptom or presenting condition GUNA's dosing guide associates with one or more remedies, for symptom-led (rather than lab-led) prescribing. Where several remedies are listed for one symptom, GUNA's material doesn't rank them — clinical judgement, and the wider presentation, determines which is the better fit. A handful of the remedies named in GUNA's own reference (Dopamine, Oxytocin, and Parathyroid Hormone) aren't currently part of our individual remedy range; they're included below for completeness and left unlinked, consistent with how we've handled molecules outside our catalogue elsewhere in this series.
A–Z Symptom Correlations
| Symptom / condition |
Associated remedy(ies) |
| Abdominal pain (cramp-like) |
IL-5 |
| Abdominal swelling |
IL-11 |
| Acute and chronic stress |
IL-8 |
| Acute inflammatory diseases |
Anti IL-1
|
| Aging |
IL-2, FGF, IGF-1, PDGF, ACTH, Beta-Estradiol, FSH, LH
|
| Allergic syndromes |
IFN-γ, IL-12
|
| Allergies |
IL-12, IFN-γ, IL-13 |
| Allergy-induced hyperlacrimation |
IL-12 |
| Appetite control |
CNTF |
| Appetite disorders (excessive appetite) |
IL-1, IL-6
|
| Articular pain |
IFN-α |
| Articular symptoms (painful-degenerative) with limited movement |
FGF |
| Asthenia |
IL-1, IL-7, IFN-α, IFN-γ, ACTH, Parathyroid Hormone |
| Asthenia and drowsiness |
IL-9 |
| Autism |
BDNF |
| Autoimmune diseases |
TGF-β1 |
| Basic regulation in patients undergoing immunotherapy |
IL-11 |
| Basic therapy for autoimmune diseases |
IL-4 |
| Blurred vision with scintillating scotomas |
EGF |
| Bone pain |
Calcitonin |
| Bruise-induced pain |
IL-5 |
| Burning sensation in the mouth |
IL-2 |
| Catarrh |
IL-8 |
| Cerebral aging |
BDNF, CNTF
|
| Chapped skin |
EGF |
| Chemotaxis activation |
IL-8 |
| Chronic bacterial infections |
TNF-α |
| Chronic catarrh |
IL-9 |
| Chronic Fatigue Syndrome |
Dopamine |
| Chronic inflammations |
TGF-β1 |
| Chronic inflammatory diseases |
IL-4, IL-10
|
| Chronic pain syndromes |
IL-10, Beta-Endorphin, TGF-β1
|
| Chronic viral infections |
IFN-γ |
| Chronic stress |
ACTH |
| Cicatrisation difficulty |
FGF |
| Circadian rhythm and organ function alterations |
Melatonin |
| CNS and PNS diseases |
NT3, NT4
|
| Complementary treatment for tumours |
Somatostatin, IL-12, IFN-γ, IL-2, Melatonin, TNF-α
|
| Confusion at night with sleep disorders |
TNF-α |
| Constipation and flatulence |
IL-5 |
| Cramp-like pain |
Parathyroid Hormone |
| Crohn's Disease |
IL-10 + Anti IL-1
|
| Damage to the myelin sheath |
G1 (GD3 Ganglioside) |
| Decreased sexual arousal |
Dopamine |
| Decreased sexual satisfaction |
Oxytocin |
| Diet disorders |
Serotonin |
| Digestive disorders |
IL-3 |
| Drug addiction |
Dopamine |
| Early aging |
IL-3 |
| Erratic pain |
IL-3 |
| Erythroid proliferation disorders (synergy with erythropoietin) |
IL-9 |
| Feeling of heaviness in the epigastrium with soreness |
EGF |
| Female hormone cycle disorders and infertility |
Beta-Estradiol, FSH, LH, Progesterone
|
| Fever |
Anti IL-1
|
| Food intolerances |
IL-12 |
| Gastric acid hypersecretion |
EGF |
| General sickness |
IL-2, IL-6
|
| Growth and development disorders |
IL-7, IL-11
|
| Growth disorders |
IGF-1, T4
|
| Haemopoiesis disorders |
IL-3, IL-11
|
| Headache |
Serotonin |
| Hot flushes |
Beta-Estradiol |
| Hypersensitivity to pain |
EGF |
| Hyperparasympathicotonia |
ACTH |
| Hypersympathicotonia |
Melatonin |
| Hyperthyroidism |
Somatostatin |
| Hypothyroidism |
T3 |
| Immune response triggered in chronic and autoimmune diseases |
GCSF |
| Immunodeficiencies |
IL-2 |
| Intermenstrual spotting |
Progesterone |
| Intestinal parasitosis |
IL-5 |
| Itching |
EGF |
| Itching and burning sensation |
IL-10 |
| Jet lag |
Melatonin |
| Lack of attentiveness |
Dopamine |
| Lack of sexual desire |
Dopamine |
| Localised inflammations |
IL-2 |
| Loss of appetite |
ACTH |
| Loss of strength in limbs, easy tiredness |
NGF |
| Low female libido |
FSH, Oxytocin, Dopamine |
| Low male libido |
LH, Dopamine |
| Memory disorders |
NGF, IGF-1, IL-11
|
| Memory loss |
IL-3 |
| Menstrual pain |
Progesterone |
| Mental fatigue |
IL-4 |
| Mental strain |
Dopamine |
| Mental tiredness |
BDNF, G1 (GD3 Ganglioside)
|
| Mood disorders |
NGF, NT3, NT4, Oxytocin, Dopamine |
| Mood disorders with unstable mood |
Melatonin, Serotonin, Tryptophan
|
| Muscle weakness |
G1 (GD3 Ganglioside), NT3, NT4, Prolactin
|
| Myalgia and stiffness (especially in the morning) |
TNF-α |
| Mitogenic activity |
PDGF |
| Nasal obstruction and nose itch |
IL-12 |
| Nervous breakdown and tiredness |
IL-7, IL-11
|
| Neuralgic pain |
NGF, IL-9
|
| Neurasthenia |
T4, TSH
|
| Neurological damage (developmental or post-injury) |
BDNF, CNTF, NT3, NT4
|
| Osteoporosis |
Calcitonin |
| Outcome of psychic shock |
BDNF |
| Ovarian polycystosis |
FSH, Progesterone
|
| Pain of diverse origins |
Beta-Endorphin |
| Pain syndromes |
Beta-Endorphin, Anti IL-1, NT4
|
| Painful muscular spasms |
IFN-α |
| Paroxysmal sneezing |
IL-12 |
| Physical asthenia |
T4 |
| Premenstrual syndrome |
Progesterone, Beta-Endorphin
|
| Productive cough |
IL-8 |
| Psoriasis |
IL-11, IL-4, IL-10
|
| Pulsating pain |
IL-7, IL-11
|
| Pyrosis and gastric acid hypersecretion |
IL-11 |
| Recurrent infections |
IL-7 |
| Recurrent nighttime cough |
IL-12 |
| Recurrent viral infections |
IFN-α |
| Reddened mucous membranes |
IL-10 |
| Recurrent respiratory infections with IgA deficiency |
IL-5 |
| Sadness and loss of interest |
NGF |
| Sagging skin |
Beta-Estradiol |
| Sensitivity to infectious diseases |
GCSF |
| Sensitivity to viral infections |
IL-2 |
| Side effects of chemotherapy, radiotherapy and antiviral treatments |
IL-3 |
| Sight disorders |
CNTF |
| Skin aging |
EGF, FGF
|
| Skin eruptions |
IL-3 |
| Skin rashes |
EGF |
| Skin thinning and ulcers |
NGF |
| Sleep disorders |
Melatonin, Tryptophan, IL-1
|
| Social phobia |
Oxytocin |
| Spastic cramp-like pain |
IL-4 |
| Spastic muscle pain |
IFN-γ |
| Stiff muscles |
BDNF |
| Stress |
BDNF, Beta-Estradiol, Melatonin
|
| Subacute pain syndromes |
IL-2, Beta-Endorphin
|
| Sudden pain with numbing |
IFN-α |
| Supportive treatment during delivery |
Oxytocin |
| Supportive treatment of Autism |
Oxytocin |
| Supportive therapy for Parkinson's disease |
Dopamine |
| Swollen and reddened skin |
IL-12 |
| Tendency toward overweight |
T3 |
| Tingling sensation and numbness in hands and feet |
BDNF |
| Vertigo with vomiting |
IL-3 |
| Vomiting with loss of appetite |
IL-10 |
| Water retention |
IL-9, TSH
|
| Weariness, adynamia |
IL-2 |
| Wrinkles |
PDGF |
Reading This Alongside the Rest of the Series
This index is deliberately the last article in our GUNA Method / Cytokines / Biotherapy Dosing set — it's the practical, symptom-first lookup that sits on top of the theory in the GUNA Method articles, the molecule-by-molecule detail in the Cytokines articles, and the dosing mechanics and aetiological pairing tables in Part 1 of this series.
Featured products
Guna · Growth FactorGuna BDNFLow-dose Brain-Derived Neurotrophic Factor, used for cerebral aging, stress and neurological support.
Guna · NeuropeptideGuna Beta-EndorphinLow-dose Beta-Endorphin, used for pain of diverse origins and premenstrual syndrome.
Explore the full Guna range — GUNA Method, Cytokines and other GUNA-Method products.
Not sure which remedy is right for you?
Try our Natural Remedy Finder, or contact our team for guidance.
Related reading
Source: GUNA, biotherapy dosing guide — full symptom/syndrome/pathological condition correlations index.
Tags: Deep Guna Research, Guna Articles, Biotherapy Dosing
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