Secreting Gland:
Anterior Pituitary Gland

Overview

Adrenocorticotropic Hormone (ACTH) is a key hormone produced by the anterior pituitary gland that regulates the activity of the adrenal cortex. It stimulates the production and release of cortisol and other adrenal hormones, which play essential roles in the body's response to stress, immune regulation, metabolism, inflammation, and energy production.

Within GUNA's Low Dose Medicine philosophy, Guna ACTH is traditionally used to support the physiological regulation of the hypothalamic-pituitary-adrenal (HPA) axis. Rather than replacing endogenous hormone production, it is intended to encourage the body's natural endocrine regulation and adaptive stress response.

Primary Physiological Actions

ACTH plays an important role in:

• Supporting adrenal gland function.
• Regulating cortisol production.
• Supporting the body's response to physical and emotional stress.
• Helping regulate carbohydrate, protein, and fat metabolism.
• Supporting immune system regulation.
• Assisting the body's natural inflammatory response.
• Supporting energy production and vitality.
• Maintaining communication within the hypothalamic-pituitary-adrenal (HPA) axis.
• Supporting neuroendocrine balance.

Traditional Indications

Within biological and bioregulatory medicine, Guna ACTH is traditionally considered where support of adrenal regulation and stress adaptation is desired, including:

• Chronic stress.
• Fatigue.
• Burnout.
• Reduced stress resilience.
• Adrenal dysregulation.
• Neuroendocrine imbalance.
• Recovery following prolonged illness.
• Chronic inflammatory conditions.
• Immune regulation programmes.
• General endocrine support.

Commonly Used by Practitioners For

• Adrenal support.
• Stress management.
• Chronic fatigue.
• Burnout recovery.
• Neuroendocrine regulation.
• Immune support.
• Energy optimisation.
• Recovery following chronic illness.
• HPA axis regulation.
• Healthy ageing programmes.

Common Complementary Remedies

Depending on the clinical presentation, Guna ACTH is commonly combined with:

• Cortisol D6 – adrenal hormone regulation.
• Adrenal Gland D6 – adrenal support.
• Hypophysis suis – pituitary regulation.
• Hypothalamus suis – neuroendocrine regulation.
• Thyreoidea suis – broader endocrine support.
• Coenzyme Compositum – cellular metabolism and energy production.
• Ubichinon Compositum – mitochondrial support and vitality.
• Engystol – immune regulation.
• Neurexan – support during periods of stress and nervous tension.

Dosage

15–20 drops twice daily.