Secreting Gland:
Corpus luteum during the menstrual cycle and the placenta during pregnancy.

Overview

Progesterone is one of the body's principal female sex hormones and plays a central role in regulating the menstrual cycle, preparing the uterus for implantation, maintaining pregnancy, and supporting normal breast development. It also influences mood, sleep, the nervous system, bone metabolism, and immune regulation.

Within GUNA's Low Dose Medicine philosophy, Progesterone D6 is traditionally used to support the body's physiological regulation of progesterone signalling. Rather than replacing endogenous progesterone, it is intended to provide a regulatory stimulus that encourages normal endocrine function and hormonal balance.

Primary Physiological Actions

Progesterone plays an essential role in:

• Preparing the endometrium for embryo implantation.
• Supporting the maintenance of pregnancy.
• Preparing the mammary glands for lactation.
• Regulating the menstrual cycle, particularly the luteal phase.
• Balancing the effects of oestrogen.
• Supporting normal ovulation and corpus luteum function.
• Modulating immune tolerance during pregnancy.
• Supporting healthy neurological function, mood, and sleep.
• Contributing to normal bone metabolism and connective tissue health.

Traditional Indications

Within biological and bioregulatory medicine, Progesterone D6 is traditionally considered where support of female hormonal regulation is desired, including:

• Premenstrual syndrome (PMS).
• Menstrual irregularities.
• Luteal phase insufficiency.
• Dysmenorrhoea (painful menstruation).
• Intermenstrual bleeding.
• Polycystic Ovary Syndrome (PCOS).
• Perimenopausal hormonal imbalance.
• Menopausal support.
• Fertility support where progesterone regulation is a consideration.
• Functional oestrogen dominance.

Potential Clinical Applications

Practitioners may incorporate Progesterone D6 into broader endocrine and reproductive protocols for:

• Hormonal balancing programmes.
• Female fertility support.
• Menstrual cycle regulation.
• Perimenopause and menopause support.
• Premenstrual symptoms.
• Hormone-related mood fluctuations.
• Endocrine regulation protocols.
• Healthy ageing programmes for women.

Common Complementary Remedies

Depending on the clinical presentation, Progesterone D6 is commonly combined with:

• Ovarium suis – ovarian support.
• Hypophysis suis – pituitary regulation.
• Hypothalamus suis – neuroendocrine regulation.
• FSH D6 – follicular development and ovarian function.
• LH D6 – ovulation and corpus luteum support.
• Prolactin D6 – pituitary and reproductive hormone regulation.
• Thyreoidea suis – broader endocrine support.
• Coenzyme Compositum – cellular metabolism and endocrine regulation.
• Ubichinon Compositum – mitochondrial and cellular energy support.

Dosage

15–20 drops twice daily, or as directed by a healthcare practitioner.